Case Study for Comparative Effectiveness Research

Executive Summary: In recent years, the Institute of Medicine and other entities have called for a large expansion of comparative effectiveness research (CER) in the United States. CER involves a comparison of the effectiveness of two or more different health care interventions when administered to a diverse population of patients in the real world. The hope is that generating and using additional information on comparative effectiveness will lead to improved decisions about health care by U.S. patients, physicians, health care purchasers, and others, thereby improving the effectiveness of care and potentially restraining the growth in U.S. health care costs…



Case Study for Comparative Effectiveness Research


Introduction: Unsustainable costs and system-wide inefficiencies have led experts to call for a fundamental overhaul of the entire U.S. health care system. The United States spends more per citizen on health than any other country in the world. In 2007, total U.S. health expenditures reached $2.2 trillion ($7,421 per person), which translates to 16.2 percent of the nation’s gross domestic product (GDP). At current growth rates, total health expenditures in the United States will account for 25 percent ofGDP by 2014…
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